Advances in Lung Stem Cell Research

Researchers at Center for Regenerative Medicine at Brigham and Women’s Hospital (BWH) in Boston, Massachusetts found that the human lung stem cell is self-renewing, playing an important role in regenerating tissue and may also help in the repairing of damaged lung cells. They also found that the stem cell can actually duplicate the various structures of the lung, including alveoli, bronchioles, and pulmonary vessels.

This report in this weeks New England Journal of Medicine challenges current scientific thinking about lung cells. Until this study, scientists thought there were no cells in the lung that could differentiate into the various types of lung cell.

This is just the beginning of research that is likely to lead to completely new treatments that repair and regenerate damaged lung tissue in COPD patients.

For more information, go to:
http://www.medicalnewstoday.com/articles/225017.php


29 Responses to “Advances in Lung Stem Cell Research”

  1. Paula Campbell says:

    This is the best news I have heard in a very long tme. I am a 50 year old female with COPD that is currently being managed with medication. This news give me hope that I may actually have an opportunity to see my youngest daughter age 14, graduate from High School, get married and have children. Thank you so much for the work you guys are doing and please continue your work. God Bless

    Paula Campbell

  2. LaVonne says:

    YIPPPPEEEE!!!!!!

  3. anna says:

    this is great news,

  4. Al says:

    Many if not most of us will no longer be alive by the time it is available here in the U.S. It takes years and years to reach your doctors office

    Many are looking at other countries for treatment because of this. The benefits of treatment outweighs the risk of dieing

    • Mikos says:

      Hi Al. This issue of looking abroad, (from the USA), for treatment of diseases is not an uncomon event; AIDS treatments in France during the 80s and 90s comes to mind. I do feel a great sense of hope from this research and I will continue to monitor the research. I wouldn’t mind travelling ANYWHERE for effective treatment/cure.

  5. anna says:

    this is wonderful news, i hope this is available soon . i am currently on oxygen and was diagnosed in “04″ i would so love to watch my 4 yr old grand daughter grow up and go to high school and on to college. i know its a big wish but, maybe ?

  6. Linda says:

    I was also diagnosed in “04.” I had only been married a year. We are newlyweds and I find out I have an aweful disease. I so would like to able to do the things we used to do before I beame ill.

  7. Al says:

    Now is the time for those with COPD
    to really start to put pressure on the
    FDA, to approve the unfettered use of Lung Stem Cell human clinical
    studies! Lung stem cells do what they’re supposed to do, even better
    than adult stem cells, from other parts of the body. They come already
    educated! They just need to be populated in numbers to do the job
    of repair and regeneration. I’m not
    one who really tries to rally anything,
    but this spawns a new lease on life,
    and we should do all that we can to
    put a fire under the FDA. People are
    dying, when there’s a chance to LIVE!!!

  8. fran says:

    where can you get lung stem cells now, what countries
    are ahead? It is too long to wait here when there is
    help.

  9. Rosemary Osnato says:

    My brother is now on oxygen due to copd. He has had his first stem cell (Adult treatment) this week and he is receiving retinoic acid treatments through a nebulizer. His condition is not in the late stages so we are hoping that the adult stem cells will buy him the time it will take for lung stems cell treatments to be developed. We all need to write, email, lobby the FDA to inable our US (talented and well educated) doctors to save American who have this horrible and deadly illness. It was also our American tobacco companies who are largely responsible. Now the FDA is denying the American people a stem cell cure. We all know the real reasons for this political power and money. Gingrich has already said that if he is President that embryonic stem cell treatment would never be made legal. Drug companies do not want to see cures only treatments that they control. We must all fight to save our lives and the lives of those we love.

    • Lynne says:

      Rosemary O
      What Country/ treatment centre is your brother undergoing his stem cell treatment?

      • Debra says:

        Would like to know if your brothers treatment was in the states as we talked to a Dr. in Fla. about this procedure.Has the treatment helped and is further treatment necessary? Best of luck to him!

    • Judy Perley says:

      Where does your brother get “adult stem cell “treatments in U.S.? Thank you so much
      Judy

    • jean hiarker says:

      where did you brother get his stem cells? am looking for a clinic for my own stem cell use everone in the clinic say they are the best. i need a third party opinion. thanks

  10. Carlton D. Trotman says:

    2 years plus ago I had abdominal surgery (abdominal aorta)and smoked my last cigarette before entering the hospital Smoked for 60 plus years. Shortly after hospital discharge no withdrawal sysptoms BUT diagnosed with COPD. With walking, stair climbing and/o, minor exertion shortness of breathe begins/lasts for a minute. No coughing. mucus or phlegm. Using inhalants regularly – Ambuterol for example – but really haven’t reduced shortness of breath.

  11. Carlton D. Trotman says:

    BY the way, I’m 79 years old, worked from age 12 until 2004 (six months temporary assignment with state of PA 11/2006 – 5/2007) Nothing except possibility with a community organization.

    Any suggestions re: returning to work? No problem sitting. I have extensive teaching experience (college level) and 25 years pluse in drug and alcohol prevention and treatent. dealt primarily with heroin addicts in prison/on parole. Last ft emplomet in ’04 was about a year workiking with adjudicated youth.

  12. sue says:

    HELLO
    I HAVE COPD I WAS WATCHING A DOCTOR SHOW AND THERE A DOCTOR ON DID NOT GET HIS NAME AND THEY WHERE TALKING ABOUT A STEM CELL . I ADOPTED A LITTLE GIRL I HAD HER SINCE SHE WAS 7 MONTHS OLD . I DO GIRL SCOUT WITH HER THE BEST I CAN . I WOULD LOVE TO WALK TO THE MALL WITH HER AND GO ON TRIPS WITH OUT STOP THAT I CAN NOT BREATH I SCARE HER SOME TIME . I AM IN GOOD HEALTH OTHER THEM MY LUNGS PLEASE CAN YOU HELP ME AND MY DAUGHTER . I WOULD LOVE TO BREATH AGAIN WITH OUR THE MEDICINE AND BREATHING MACHINE I HAVE TO TAKE WITH ME ALL THE TIME . I WOULD TO SEE IF YOU CAN HELP ME .
    SBONIN849@MINDSPRING.COM

  13. Kathy Smith says:

    I too would be willing to try stem cell to help my COPD. I am only 59 and would love to be able to do things with out getting short of breath.I love to garden but due to my breathing it is hard to do.I am in decent health except for some circulation problems and now osteoporosis due to some of the treatments from this horrible disease.(the steroids and other things also from the smoking ,I have quit for 5 yrs now)I was diagnosed in 2005 and I hate not being able to do the things I used to do.I was very active and i hate not being able to go camping or bowling or even huntinf and fishing now.Maybe someday ……..

  14. Everett Byrom says:

    I was diagnosed with bronchitis in 1965 and it has advanced to COPD in it’s final level.I have been medically retired since 9,2011 and now am confined to a scooter and O2 constantly. My M.D. has kept me up and going and when Daxas came out he added it to my regime of meds for treatment to go with Spireva and Symbicoet. I have not had an acute event of excerbation since then.I have to order my meds thru Canada pharmacies and from overseas. The FDA and big Pharma has everything so expensive in the USA that I wouldn’t be able to buy the necessary meds to exist not that they give a darn. My Combivent is so expensive here that I can buy twelve for what one costs here in the U.S. I urge you all to bombard the FDA and your pharmacies with the demand for stem cell treatmant through it’s research and for less expensive meds. The more of us that raise hades the more they will listen. The government doesn’t hear the quiet souls any more. Tell your family and church to join in the fight.

  15. cully lee says:

    My dad has COPD and the Doctors says they can’t do anything for him. Not once did they mention stem cell . What Hospital does stem cell for COPD ?

    • Lulu says:

      There is a clinic in Tampa Florida that is doing some work with stem cells for COPD. They harvest them from your own blood or your bone marrow. Sounds exciting. Of course insurance doesn’t cover this treatment.

  16. Thomas Lesick says:

    I would like to know what doctors in the USA are doing stem cell theraphy for COPD patients out of country ?

  17. Bea Craddock says:

    why is it taking so long for the doctors in the U S to get a grip on this. Copd patients need help yesterday. We need help now.

  18. Bob says:

    I have COPD for the last 7 years. So far no oxegen but moving in that direction. I am very knowledgeable about the heart stem cell and seen the success in the phaze ii trials on humans. What country is currently doing lung stem. When will BWH be getting into human testing?

  19. rebecca s. tudor says:

    Give us info from rosemary osnato’brother who is receiving stem cell treatment for cops. We need to know where, doctor named, and hospitals. Please inform us immediately. Thank you

  20. Cornelious says:

    I suffer from COPD and have been told the same, no cure, no hope. I’d like to know where to get stem treatment also.

  21. sue harris says:

    Hi I have been under a respitory consultant for 18 months and still do not have a diagnosis.I am experiemcimg shortm
    ness of breath and some times am ok and others really breatles during mild excercise. My breat test was within normal limits and the consultant referred me to a cardiologist . he does not think it it my heart. I have had the results of a chest scan which does show mild damage to my lungs. When i did a six minute walking test my oxygen sats dropped to 85 and yet they are saying the lung damage cannot account for these results. I dont know where i am and wish i could get a diagnosis. I do feel my problem is due to copd. I am feeling very low in mood and am frequently tearful. I am off work at the moment but will not get benefits as the chest x ray shows mild damage. I am a psychiatric nurse on a busy ward and can walk 1-2 miles a shift. I dont know what i am going to do. Wish i could feel hopeful for the future.

  22. Joe Mowry says:

    Have now been on O2 since Aug 2011. Severe COPD on LTOT 2 LPM pretty much 24/7. Like others here I to and hoping that there will soon be treatments available from the Adult Stem Cell research that has been done. The extensive studies/research that was done at Brigham And Women’s and Weill Cornell, and were funded in part by the National Institute of Health (NIH) and proved (using mice) that it was possible to force the lungs to regenerate with the use of Adult Lung Stem Cells. The research concluded with reports in 2011, that are available on line.
    I have been searching and searching for all the information I can find on Lung Regeneration research.
    I can only make the assumption that Big Pharma (drug companies)that hospitals especially (teaching)receive big $$) to support research. Far more then the NIH gives. Developing the research that produces a viable treatment for all of us that suffer from COPD would take Billions of dollars that is now spent and continue to be spent on drugs that don’t do much more then keep us able to breath a bit easier (and sometimes not that well) And the teaching hospitals/universities like receiving the Big Pharma money.
    I am however, an optimist! And will continue to search for viable Adult Stem Cell Research that may be able to help. I for one would opt to be a guinea pig in testing possibly what they have already done with mice using human Adult Lung Stem cells.
    For me at this time 6 stairs, 50-100 feet my O2 saturation will drop to 85-75 and have to stop and recover. So being the guinea pig with possibility of gaining back more lung function. Quality of life right now is just soso, and will take the risk gladly.
    Good luck to all.

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